Operando Spectroscopy of a Solid-Liquid-Gas Reaction System: Heterogeneous Asymmetric Hydrogenation of Ketones on Chirally-Modified Platinum Catalyst

Surface processes occurring at a chirally-modified Pt-catalyst during asymmetric hydrogenation have been monitored using operando ATR-IR spectroscopy. Achieving essentially the same catalytic activity and enantioselectivity as in a conventional semi-batch reactor, our analytical set-up provides spectroscopic data facilitating a molecular level understanding of the catalytic cycle under realistic working conditions.