OD11 Rhodium-Catalyzed Regio- and Stereoselective Hydrothiolation of Thiols with Alkynes

Monday, June 6, 2011: 2:50 PM
Ambassador Ballroom 1 (Detroit Marriott Hotel at the Renaissance Center )
Yong Yang and Robert M. Rioux, Chemical Engineering, Pennsylvania State University, University Park, PA
A new general and efficient Rh-based catalyst system has been developed that allows highly regio- and stereoselective synthesis of various (E)-isomer vinyl sulfides from a wide range of thiols and alkynes under mild conditions.  These results extend the application of rhodium catalysis for regio- and stereoselective organic synthesis.

Extended Abstracts: